Selected Publications (Click to read On PubMed)

Li S, Ma F, Yokota T, Garcia G Jr, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Ten Hoeve J, Arboleda VA, Bloom J, Dillon BJ, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. JCI Insight. 2020 Dec 7;. doi: 10.1172/jci.insight.145027. [Epub ahead of print] [PMID: 33284134]


Yang H, Sun L, Cai W, Gu J, Xu D, Deb A*, Duan J*. DDR2, a discoidin domain receptor, is a marker of periosteal osteoblast and osteoblast progenitors. Journal of Bone and Mineral Metabolism. 2020 May 15;. doi: 10.1007/s00774-020-01108-y. [Epub ahead of print] [PMID: 32415375]. (*Co-corresponding authors) 

Wu R, Ma F, Tosevska A, Farrell C, Pellegrini M, Deb A. Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight. 2020 Nov 12:140628. doi: 10.1172/jci.insight.140628. Epub ahead of print. [PMID: 33180747]

Yokota T, McCourt J, Ma F, et al., Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury, Cell (2020), https://doi.org/10.1016/j.cell.2020.06.030 [PMID: 32621799]

Deb A. How Stem Cells Turn into Bone and Fat. N Engl J Med. 2019 Jun 6;380(23):2268-2270. doi: 10.1056/NEJMcibr1905165. [PMID: 31167059; PMCID: PMC6901025]

Huo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu H. Enhancement of β-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing NaV1.5 expression in mice. Heart Rhythm. 2019. S1547-5271(19)30456-4. [PMID: 31125668]​

Shigeta A, Huang V, Zuo J, Besada R, Nakashima Y, Lu Y, Ding Y, Pellegrini M, Kulkarni RP, Hsiai T, Deb A, Zhou B, Nakano H, Nakano A. Endocardially Derived Macrophages Are Essential for Valvular Remodeling. Developmental Cell. 2019 Mar;48(5):617-630.e3. Epub 2019 Feb. [PMID: 30799229]


Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans. G3 (Bethesda). 2018 Nov;8(11):3499-3506. [PMID: 30201759]

Yu J, Seldin MM, Fu K, Li S, Lam L, Wang P, Wang Y, Huang D, Nguyen TL, Wei B, Kulkarni RP, Di Carlo D, Teitell M, Pellegrini M, Lusis AJ, Deb A, Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity. Circulation Research. 2018;123:73–85; [PMID:29691232]

Foulquier S, Daskalopoulos EP, Lluri G, Hermans KCM, Deb A, Blankesteijn WM. Wnt signaling in cardiac and vascular disease. Pharmacological Reviews. 2018; 70(1):68-141. [PMID:29247129]

 

Lluri G., Renella P., Finn J., Vorobiof G., Aboulhosn J., Deb A.,  Prognostic Significance of Left Ventricular Fibrosis in Patients With Congenital Bicuspid Aortic Valve. The American journal of Cardiology (2017); 120(7):1176-1179.

Monaghan, M. G., Holeiter, M., Brauchle, E., Layland, S. L., Lu, Y., Deb, A., Abhay, P., All, N., KatJa, S.,  Schenke-Layland, K. Exogenous miR-29B Delivery Through a Hyaluronan-Based Injectable System Yields Functional Maintenance of the Infarcted Myocardium. Tissue Engineering Part A, 2017

 

Seldin, M. M., Kim, E. D., Romay, M. C., Li, S., Rau, C. D., Wang, J. J., Krishnan, K.C., Wang, Y., Deb, A.,  Lusis, A. J. A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American Journal of Physiology - Heart and Circulatory Physiology, 2017; 312(4): H728-H741.

Pillai I, Li S, Romay M, Lam L, Lu Y, Jie Huang, Dillard N, Zemanova M, Rubbi L, Wang Y, Lee J, Xia M, Liang O, Xie Y, Pellegrini M, Lusis A, Deb A. Cardiac fibroblasts adopt osteogenic cell fates and can be targeted to attenuate pathological heart calcification. Cell Stem Cell, 2017; 20(2):218-232 [epub] [Highlighted by Science magazine]

Murray IR, Baily J, Chen WCW, Dar A, Gonzalez ZN, Jensen AR, Petrigliano FR, Deb A*, Henderson NC*. Skeletal and Cardiac Muscle Pericytes: Functions and Therapeutic Potential. Pharmacology and Therapeutics, 2017; 171:65-74  *corresponding author/senior authors

Wang Z,  Zhang X,  Ji Y, Zhang P, Deng K, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang Y, Li S, Cass A, Vondriska V, Li G, Deb A, Srivastava D, Yang H, Xiao X, Li H, Wang YA long non-coding RNA defines an epigenetic checkpoint for cardiac hypertrophy. Nature Medicine. 2016; 22 (10):1131-1139 [PMCID 5053883]

Brumm A, Nunez S, Doroudchi M, Kawaguchi R, Duan J, Pellegrini M, Lam L, Carmichael T, Deb A*, Hinman J*. Astrocytes can adopt endothelial cell fates in a p53 dependent manner. Molecular Neurobiology, [2016] *corresponding authors

 

Deb A. Wang Y. Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation, 2015; 131(17):1468-1470

Ubil E, Duan J, Pillai I, Rosa-Garrido M, Wu Y, Bargiacchi F, Lu Y, Stanbouly S, Huang J, Rojas M, Vondrinska T, Stefani E & Deb A. Mesenchymal-endothelial transition contributes to cardiac neovascularization.
Nature,  2014; 514:585-90 [PMID 25317562]